Chromosome specimen maker 16-Samples Metaphase Harvester HANABI-PI does the processing of cell harvesting from the cultured cell automatically, simplifying a complicated process and producing uniform cells. The main operation of Metaphase Harvester is the constant temperature centrifugal separator structure, a hypotonic treatment using pre-heated hypotonic solution that enable fixation processing with cooled fixative solution. The centrifugal separator section is located at the center with 4 sets of centrifugal sections, 4 tubes per set, capable of producing 16 specimens at one time by injecting solutions and exhaust solutions. By using the HANABI-PI, a large amount of stable chromosome specimens can be produced enabling cell harvesting.